MailEnable uses the Microsoft Management Console for administration. Microsoft Management Console (MMC) uses data files files with the .msc extension. There is a shortcut to the msc file created under the "Mail Enable" program group.

The administrator on the server can access MailEnable under the Start > Program Files menu. For versions older than version 7 it is also possible to open the MSC file directly from the Mail Enable\Bin directory. If using version 7 or later of MailEnable the shortcut can be found under the Mail Enable\Admin directory.